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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCF2L
All Species:
15.45
Human Site:
S250
Identified Species:
37.78
UniProt:
O15068
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15068
NP_001106203.1
1137
128109
S250
Q
T
A
Q
M
L
Q
S
F
G
T
E
L
A
E
Chimpanzee
Pan troglodytes
XP_509745
1123
126012
E222
M
L
Q
S
F
G
T
E
L
A
E
T
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001103476
1325
144488
E222
M
L
Q
S
F
G
T
E
L
A
E
T
E
L
P
Dog
Lupus familis
XP_542673
1152
129437
D220
C
A
H
T
E
K
K
D
K
A
K
E
D
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64096
1149
129131
A250
Q
T
A
Q
M
L
Q
A
F
G
T
E
L
A
E
Rat
Rattus norvegicus
Q63406
1149
129391
A250
Q
T
A
Q
M
L
Q
A
F
G
T
E
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515228
1441
162747
S317
Q
T
A
Q
M
L
Q
S
F
G
T
E
L
A
E
Chicken
Gallus gallus
XP_416947
1249
142097
S294
Q
T
A
Q
I
L
Q
S
F
G
T
E
L
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922183
1311
148260
S320
K
T
A
Q
T
L
Q
S
F
G
T
E
L
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392741
1340
152741
S527
D
V
S
F
A
L
D
S
F
T
R
R
L
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
69.5
81.9
N.A.
85.9
85.5
N.A.
60.5
68.4
N.A.
51.4
N.A.
N.A.
28
N.A.
N.A.
Protein Similarity:
100
95.5
74.9
87.3
N.A.
91.4
91.3
N.A.
69.5
79.1
N.A.
64.9
N.A.
N.A.
44.4
N.A.
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
100
0
0
13.3
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
60
0
10
0
0
20
0
30
0
0
0
70
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
20
0
0
20
70
20
0
70
% E
% Phe:
0
0
0
10
20
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
0
0
0
60
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
10
0
10
0
10
0
0
0
0
% K
% Leu:
0
20
0
0
0
70
0
0
20
0
0
0
70
20
0
% L
% Met:
20
0
0
0
40
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% P
% Gln:
50
0
20
60
0
0
60
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% R
% Ser:
0
0
10
20
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
60
0
10
10
0
20
0
0
10
60
20
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _